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Published on: January 15, 2017
Stroke in young adults: a study from a university hospital in north India
Man Mohan Mehndiratta1, Puneet Agarwal, Kaushik Sen
1Department of Neurology, G.B. Pant Hospital, New Delhi 110002, India. mmehndi@vsnl.com
Insights
Stroke significantly impacts young individuals, with hypertension and smoking being key risk factors. Cardioembolic and atherosclerotic causes dominate ischemic stroke in this demographic.
Area of Science:
- Neurology
- Vascular Medicine
- Public Health
Background:
- Stroke is a leading cause of disability and death, presenting a significant socioeconomic challenge, particularly in young populations and developing nations.
- Understanding stroke in young individuals is crucial due to its disproportionate impact on morbidity and mortality.
Purpose of the Study:
- To investigate the clinical characteristics, stroke types, and etiological factors of stroke in young patients.
- To identify prevalent risk factors and common causes of stroke in a young demographic.
Main Methods:
- Retrospective analysis of cerebrovascular accident (CVA) cases admitted to a neurology department between 1988 and 1997.
- Categorization of stroke types (ischemic stroke, intracerebral hemorrhage) and etiological factors.
Main Results:
- Young stroke patients constituted 13.5% of all CVA cases.
- Ischemic stroke was predominant (85.8%), with cardioembolic (29.4%) and atherosclerotic occlusive disease (22%) as common causes.
- Hypertension, hypercholesterolemia, hypertriglyceridemia, and smoking were identified as major risk factors; oral contraceptives, alcohol, and drug use were infrequent.
Conclusions:
- Key stroke risk factors in young patients include hypertension, hypercholesterolemia, hypertriglyceridemia, and smoking.
- Cardioembolic stroke and atherosclerotic occlusive disease are the primary contributors to ischemic stroke in young individuals.
- Etiology remained undetermined in 10.09% of cases, highlighting the need for further research.
Background:
Stroke is one of the foremost cause of morbidity and mortality, and poses a major socioeconomic problem in young patients, especially in developing countries.
Material/Methods:
The present study was conducted in order to analyze the clinical characteristics, stroke types and etiology of stroke in young persons.
Results:
Stroke in young patients accounted for 13.5% (127/940) of all cerebrovascular accident (CVA) cases admitted to the Department of Neurology between 1988 and 1997. Ischemic stroke accounted for 85.8% of the young patients of young stroke, while 14.2% had spontaneous intracerebral hemorrhage (ICH). In cases of cerebral infarction, 29.4% of these patients (32/109) had cardioembolic stroke, followed by atherosclerotic occlusive disease in 22% (24/109), and nonatherosclerotic vascular disease in 15.6% (17/109) of patients. 13 patients had a metabolic etiology, while the cause was undetermined in 11 cases (10.09%). 17.3% of the young patients (22/127) had no risk factors, while 27.55% (35/127) had multiple risk factors.
Conclusions:
The major risk factors for stroke in our young patients were hypertension, hypercholesterolemia, hypertriglyceridemia and smoking. Oral contraceptives, alcohol and illicit drug use were infrequent risk factors, in contrast to Western studies. Cardioembolic stroke and atherosclerotic occlusive disease were the most common cause of ischemic stroke.
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