Stroke in young adults: a study from a university hospital in north India

Man Mohan Mehndiratta1, Puneet Agarwal, Kaushik Sen

  • 1Department of Neurology, G.B. Pant Hospital, New Delhi 110002, India. mmehndi@vsnl.com

Insights

Stroke significantly impacts young individuals, with hypertension and smoking being key risk factors. Cardioembolic and atherosclerotic causes dominate ischemic stroke in this demographic.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Public Health

Background:

  • Stroke is a leading cause of disability and death, presenting a significant socioeconomic challenge, particularly in young populations and developing nations.
  • Understanding stroke in young individuals is crucial due to its disproportionate impact on morbidity and mortality.

Purpose of the Study:

  • To investigate the clinical characteristics, stroke types, and etiological factors of stroke in young patients.
  • To identify prevalent risk factors and common causes of stroke in a young demographic.

Main Methods:

  • Retrospective analysis of cerebrovascular accident (CVA) cases admitted to a neurology department between 1988 and 1997.
  • Categorization of stroke types (ischemic stroke, intracerebral hemorrhage) and etiological factors.

Main Results:

  • Young stroke patients constituted 13.5% of all CVA cases.
  • Ischemic stroke was predominant (85.8%), with cardioembolic (29.4%) and atherosclerotic occlusive disease (22%) as common causes.
  • Hypertension, hypercholesterolemia, hypertriglyceridemia, and smoking were identified as major risk factors; oral contraceptives, alcohol, and drug use were infrequent.

Conclusions:

  • Key stroke risk factors in young patients include hypertension, hypercholesterolemia, hypertriglyceridemia, and smoking.
  • Cardioembolic stroke and atherosclerotic occlusive disease are the primary contributors to ischemic stroke in young individuals.
  • Etiology remained undetermined in 10.09% of cases, highlighting the need for further research.
Abstract

Related Concept Videos

Stroke: Introduction and Types01:29

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...