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Updated: Aug 13, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
Published on: July 28, 2010
RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer
R D Church1, J Yu, J W Fleshman
11Department of Surgery, Washington University School of Medicine, St Louis, MO 63110-1093, USA.
Abstract:
Cyclooxygenases (particularily Cox-2) are involved in carcinogenesis and metastatic cancer progression. The expression profiles of the cyclooxygenases and the roles they play in established tumours of similar stage remains unclear. We report that Cox-1 and Cox-2 expression is highly variable in Dukes' C tumours, and changes in Cox-1 expression may be of importance.
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