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[Sympathetic ophthalmia, one missing disease?].

P Cernea1, C Leulescu

  • 1Clinica Oftalmologică-Craiova.

Oftalmologia (Bucharest, Romania : 1990)
|January 1, 1997
PubMed
Summary
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Sympathetic ophthalmia, a rare condition, can occur after eye injuries or surgeries. Early clinical diagnosis and treatment with corticotherapy and immunomodulators can lead to a benign outcome.

Area of Science:

  • Ophthalmology
  • Immunology

Context:

  • Sympathetic ophthalmia is a rare, bilateral granulomatous inflammation of the uveal tract.
  • It typically occurs after penetrating ocular trauma or intraocular surgery.

Purpose:

  • To report the incidence, clinical presentation, and management of sympathetic ophthalmia in a series of patients.
  • To emphasize the importance of clinical diagnosis and prompt treatment.

Summary:

  • Ten cases of sympathetic ophthalmia were treated between 1992-1996, representing 0.16% of hospitalized patients.
  • Causes included corneoscleral penetrating wounds, cataract surgery complications, angle-closure glaucoma, and herpetic corneal ulcers.
  • The time from ocular trauma to sympathetic ophthalmia onset was two months in most cases.
  • Clinical presentations varied, including anterior uveitis, panuveitis, and uveopapillitis.

Related Experiment Videos

  • Pathologic examination of the enucleated eye was not specific; diagnosis relied on clinical findings.
  • Treatment with corticotherapy and immunomodulators resulted in a benign evolution.

    • Impact:

    • Highlights the persistent occurrence of sympathetic ophthalmia, underscoring it as a condition not to be underestimated.
    • Demonstrates the effectiveness of current therapeutic strategies in managing sympathetic ophthalmia.
    • Emphasizes the critical role of clinical acumen in diagnosing sympathetic ophthalmia, especially when histopathology is inconclusive.