Related Experiment Video
Updated: Aug 22, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
Vasovagal response induced by a low dose of isoproterenol infusion before tilting-up
Satoru Suwa1, Masataka Sumiyoshi, Yoriaki Mineda
1Department of Cardiology, Juntendo University Izunagaoka Hospital, Shizuoka, Japan.
Abstract:
A 56 year-old man was referred to hospital for evaluation of syncopal episodes. During head-up tilt testing, his symptom was reproduced, associated with bradycardia and hypotension, by a low dose of isoproterenol (0.02 microg. kg (-1). min(-1)) infusion in the supine position before tilting-up. Isoproterenol infusion can provoke a vasovagal response without tilting. Careful observation of the patient's hemodynamics is mandatory not only during tilting, but also in the supine position before tilting-up.
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