Related Experiment Video

Updated: Aug 22, 2026

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

[Primary malignant fibrous histiocytoma (MFH) of the small bowel presenting as an intussusception causing small bowel

Ung Ryu1, Byung Wook Lim, Jea Wook Roh

  • 1Department of Internal Medicine, Inje University College of Medicine, Goyang, Korea.

The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi
|August 27, 2004
PubMed

Insights

Adult intussusception caused by malignant fibrous histiocytoma (MFH) is rare. This case highlights MFH as a cause of small bowel obstruction, requiring surgical intervention and histological confirmation.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Adult intussusception is an uncommon cause of small bowel obstruction.
  • Malignant fibrous histiocytoma (MFH) of the small bowel is exceptionally rare.
  • Primary sarcomas are infrequent etiologies for intussusception in adults.

Observation:

  • A 75-year-old male presented with a month of vomiting and epigastric pain.
  • CT imaging revealed jejuno-ileal intussusception.
  • Surgical resection and anastomosis were performed for the obstruction.

Findings:

  • The resected specimen showed a polypoid tumor within the ileum.
  • Histological examination confirmed the tumor as malignant fibrous histiocytoma (MFH).
  • This represents a rare instance of MFH causing intussusception and small bowel obstruction.

Implications:

  • Highlights the importance of considering rare tumors in the differential diagnosis of small bowel obstruction.
  • Emphasizes the role of surgical resection and histopathology in diagnosing and managing such cases.
  • Contributes to the limited literature on malignant fibrous histiocytoma presenting as intussusception.

More Related Videos

Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib06:43

Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib

Published on: April 3, 2026

Related Concept Videos

Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Histology of the Small Intestine01:27

Histology of the Small Intestine

The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Histology of the Large Intestine01:26

Histology of the Large Intestine

The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...