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Updated: Aug 15, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Surgery for atrial fibrillation
1Department of Cardiothoracic Surgery, National Heart Centre, 17 Third Hospital Avenue, Singapore 168752.
Insights
Surgical ablation offers a cure for atrial fibrillation, the most common heart rhythm disorder. Newer, simpler procedures are now available, achieving high success rates in treating this condition.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Atrial fibrillation is a prevalent cardiac arrhythmia linked to increased morbidity and mortality.
- The Cox maze procedure is the gold standard for surgical atrial fibrillation treatment, with over 90% efficacy.
- Procedure complexity and long operating times have limited the widespread adoption of the Cox maze procedure.
Purpose of the Study:
- To review the evolution of surgical treatments for atrial fibrillation.
- To present the experience with the radiofrequency Cox maze III procedure.
Main Methods:
- Review of historical development in surgical ablation for atrial fibrillation.
- Analysis of outcomes from the radiofrequency Cox maze III procedure.
Main Results:
- The classic Cox maze procedure demonstrates high efficacy (>90%) but is complex.
- Advancements in understanding and technology have led to simpler, reproducible ablation techniques.
- Newer surgical procedures achieve approximately 80% cure rates for atrial fibrillation.
Conclusions:
- Surgical ablation is the most effective curative treatment for atrial fibrillation.
- Simpler, modern surgical ablation techniques offer a viable alternative to the classic Cox maze procedure.
- The radiofrequency Cox maze III procedure represents an important development in surgical atrial fibrillation management.
Abstract:
Atrial fibrillation is the most common sustained cardiac arrhythmia and is associated with significant morbidity and mortality. Surgical treatment is the most effective means of curing atrial fibrillation. The classic Cox maze procedure eliminates atrial fibrillation in more than 90% of patients and has remained the gold standard in surgery for atrial fibrillation. Despite being highly effective, the complexity of the procedure and long operating time associated with the operation has prevented its widespread application by surgeons. Advances in the understanding of the pathogenesis of atrial fibrillation and development of new ablation technologies have fuelled renewed interest in and development of surgical ablation procedures for atrial fibrillation. These new procedures are simpler and easily reproducible and cure atrial fibrillation in approximately 80% of patients. This article reviews the development of surgery for atrial fibrillation and our experience with the radiofrequency Cox maze III procedure.
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