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Updated: Aug 15, 2026

Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts
Published on: February 24, 2015
A remarkably efficient coupling of acid chlorides with alkynes in water
1Department of Chemistry, Tulane University, New Orleans, Louisiana 70118, USA.
Abstract:
[reaction: see text] A highly effective direct coupling of acid chloride with terminal alkynes catalyzed by PdCl(2)(PPh(3))(2)/CuI together with a catalytic amount of sodium lauryl sulfate as the surfactant and K(2)CO(3) as the base provided ynones in high yields in water.
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