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Target-controlled propofol infusion during monitored anesthesia in patients undergoing ERCP
Lorella Fanti1, Massimo Agostoni, Andrea Casati
1Division of Gastroenterology and Department of Anesthesiology and Intensive Care, Vita e Salute San Raffaele University, San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.
Gastrointestinal Endoscopy
|August 28, 2004
Summary
Target-controlled infusion of propofol offers safe and effective sedation for ERCP patients. This method ensures optimal patient comfort and recovery, with no severe complications observed during the study.
Area of Science:
- Anesthesiology
- Gastroenterology
Background:
- Target-controlled infusion (TCI) systems automate propofol delivery to maintain target concentrations.
- Evaluating TCI for propofol in ERCP sedation is crucial for patient care.
Purpose of the Study:
- To assess the efficacy and safety of propofol TCI for sedation during ERCP procedures.
Main Methods:
- 205 ERCP patients received propofol sedation via TCI by an anesthesiologist.
- Propofol target plasma concentrations ranged from 2-5 microg/mL; fentanyl was used for analgesia.
- ERCP technical difficulty was graded 1-5; discharge times were recorded.
Main Results:
- Mean propofol and fentanyl doses were 465 mg and 59 mcg.
- Propofol dose and ERCP duration correlated with procedure difficulty.
- No severe complications occurred; mean discharge time was 31 minutes.
Conclusions:
- Propofol TCI is a safe and effective sedation method for ERCP.
- Further research is needed on cost-effectiveness and non-anesthesiologist administration.