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[Incrusted cystitis with isolation of Corynebacterium group D2].
M I Fernández Natal1, F García Díez, J S Salas Valién
1Servicio de Microbiología, Complejo Hospitalario, León.
Medicina Clinica
|March 21, 1992
Summary
Encrusted cystitis caused by Corynebacterium group D2 can be effectively treated. Combining antibiotics like vancomycin with surgical removal of encrusted stones is key for successful outcomes in patients with this urinary tract infection.
Area of Science:
- Urology
- Infectious Diseases
- Microbiology
Background:
- Encrusted cystitis is a severe bladder condition.
- Corynebacterium group D2 has been identified as a causative agent.
Observation:
- Pre-existing bladder damage facilitates bacterial colonization.
- Rapid urease activity by Corynebacterium group D2 is central to pathogenesis.
- Clinical signs include cloudy, ammonium-smelling urine, alkaline pH, and ammonium magnesium phosphate crystals.
Findings:
- A combination therapy of antimicrobial agents and cystoscopic debridement of encrusted stones is effective.
- Vancomycin and teicoplanin demonstrate consistent in vitro activity and are suitable treatment options.
- Prompt identification of Corynebacterium group D2 is crucial to avoid misdiagnosis.
Implications:
- Understanding the role of urease activity aids in diagnosing encrusted cystitis.
- Effective treatment strategies involve both medical and surgical interventions.
- Vancomycin and teicoplanin offer reliable therapeutic options for this infection.