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Relationship between endoscopic nodular gastritis and Helicobacter pylori infection in children

Mandana Rafeey1, Amir Hossein Jafari Rouhi, Bab Allah Gassemi

  • 1Division of Gastroenterology, Department of Pediatrics, Tabriz Children Hospital, Tabriz University of Medical Sciences, Tabriz, I. R., Iran. mrafeey@yahoo.com

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|August 31, 2004
PubMed

Insights

Endoscopic nodular gastritis is strongly linked to Helicobacter pylori infection in children. This finding highlights the importance of testing for H. pylori in pediatric patients with this endoscopic sign.

Area of Science:

  • Pediatric Gastroenterology
  • Microbiology
  • Endoscopy

Background:

  • The association between endoscopic nodular gastritis and Helicobacter pylori infection in children requires further clarification.
  • Helicobacter pylori is a common bacterial infection affecting the stomach.

Purpose of the Study:

  • To investigate the relationship between endoscopic nodular gastritis and H. pylori infection in a pediatric cohort.
  • To determine if endoscopic findings correlate with the presence and density of H. pylori.

Main Methods:

  • A study involving 124 children undergoing upper GI endoscopy for abdominal pain.
  • Urease testing and histological examination were performed to assess H. pylori infection and gastritis severity.
  • Data on age, H. pylori status, and gastritis grade were collected.

Main Results:

  • Helicobacter pylori infection was identified in 46% of the children.
  • Endoscopic nodular gastritis was observed in 81% of H. pylori-positive children and 36% of H. pylori-negative children.
  • Nodular gastritis frequency correlated with increased age, H. pylori presence, and gastritis severity.

Conclusions:

  • Endoscopic nodular gastritis in children is significantly associated with H. pylori infection.
  • The findings suggest active chronic gastritis in children with nodular gastritis and H. pylori.
  • This association underscores the clinical relevance of nodular gastritis as an endoscopic marker in pediatric H. pylori infections.
Abstract

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