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Related Experiment Videos

Enterobiasis mimicking Crohn's disease.

Angel Fernandez-Flores1, Saleh Dajil

  • 1Service of Anatomic Pathology, Clinica Ponferrada, Leon, Spain. gpyauflowerlion@terra.es

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|August 31, 2004
PubMed
Summary

A man with abdominal pain mimicking Crohn's disease was diagnosed with a pinworm infection. Treatment with mebendazole resolved his symptoms, highlighting parasitic causes of gastrointestinal inflammation.

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Area of Science:

  • Gastroenterology
  • Parasitology
  • Internal Medicine

Background:

  • Crohn's disease is a chronic inflammatory bowel disease often presenting with abdominal discomfort and characteristic colonoscopic findings.
  • Differential diagnosis for inflammatory bowel disease includes infectious etiologies, which can mimic the clinical presentation.

Observation:

  • A 20-year-old male presented with a 2-month history of abdominal discomfort.
  • Colonoscopy revealed skip areas with ulceration, suggestive of Crohn's disease.
  • Biopsies demonstrated chronic inflammation and non-necrotizing granuloma.

Findings:

  • An adult pinworm (Enterobius vermicularis) was identified in the lumen of an uninvolved colonic segment.
  • The patient's symptoms resolved following treatment with mebendazole, an antiparasitic medication.

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Implications:

  • This case underscores the importance of considering parasitic infections in the differential diagnosis of inflammatory bowel disease.
  • Pinworm infestation can present with symptoms and endoscopic findings mimicking Crohn's disease.
  • Timely diagnosis and antiparasitic treatment can lead to complete symptom resolution.