Related Experiment Video
Updated: Aug 22, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
Free radicals: relation to tissue damage - a review
1Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, TN.
Abstract:
Free radicals are any molecules having an odd number of electrons. These molecules are highly reactive and can be generated as byproducts of normal metabolism as well as by exposure to a number of environmental factors including drugs, radiation and air pollutants. Due to the ubiquity of molecular oxygen, the oxygen metabolites superoxide anion, hydrogen peroxide, and the hydroxyl radical are frequently involved in both beneficial and detrimental free radical reactions. Intracellular enzymes and radical scavengers help to protect against tissue damage by these reactive metabolites. The extent of free radical damage to tissue depends on the nature of the radical produced and its site of generation.
More Related Videos
09:23A Protocol for Detecting and Scavenging Gas-phase Free Radicals in Mainstream Cigarette Smoke
Published on: January 2, 2012
12:15Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
Published on: May 29, 2019
Related Concept Videos
Bioactivation and Tissue Toxicity
Cellular Injury I: Introduction
Radical Autoxidation
Radical Reactivity: Overview
Radical Formation: Overview
Radicals from spin-paired molecules:
Radicals can be obtained from spin-paired molecules either by homolysis or electron transfer. While two radicals are formed in the former, an electron is added in the latter, also known...
Radical Reactivity: Electrophilic Radicals