Eliminating menstruation via medication is desired by many women, especially for military personnel. While effective, the high cost of goserelin (GnRH analogue) prevents its use, unlike cheaper oral contraceptives with more side effects.
Area of Science:
- Reproductive Medicine
- Pharmacology
- Women's Health
Background:
- Many women prefer to eliminate menstruation.
- Therapeutic amenorrhoea may benefit female military personnel.
- Current methods for inducing amenorrhoea have limitations.
Purpose of the Study:
- To review methods for therapeutic amenorrhoea.
- To compare the efficacy and side effects of different drugs.
- To assess the suitability of these methods for specific populations.
Main Methods:
- Review of existing literature on oral contraceptives, goserelin, danazol, and gestrinone.
- Comparison of drug effectiveness in inducing amenorrhoea.
- Evaluation of side effect profiles and cost-effectiveness.
Main Results:
- Continuous oral contraceptives are cheap but cause side effects like weight gain and bleeding.
- Goserelin (GnRH analogue) is highly effective with fewer side effects but is very expensive.
- Danazol and gestrinone are moderately effective with significant side effects and high cost.
Conclusions:
- Goserelin's advantages in efficacy and side effect profile are outweighed by its prohibitive cost.
- Traditional oral contraceptives remain a cheaper option despite their drawbacks.
- Further consideration of cost-effective methods for therapeutic amenorrhoea is warranted.
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