Related Experiment Video
Updated: Aug 22, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
Genetic disorders and the optic nerve: a clinical survey
Scott C N Oliver1, Jeffrey L Bennett
1Rocky Mountain Lions Eye Institute, PO Box 6510 Mailstop F731, Aurora, CO 80010, USA.
Abstract:
Genetic disorders can cause a broad range of optic nerve pathology. Clinical symptoms and examination findings of optic nerve dysfunction may provide early clues to the presence of inherited genetic disease. For many disorders, molecular genetic testing is available for the diagnosis of affected individuals and the identification of unaffected carriers. This article surveys a broad array of systemic genetic disorders affecting the optic nerve, reviewing their ocular manifestations, systemic findings, and clinical genetics.
Related Concept Videos
Photoreceptors and Visual Pathways
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Genetic Lingo
Sex-linked Disorders
