Thrombogenicity of gelatine impregnated vascular grafts--an experimental study

Acute platelet deposition on a knitted Dacron graft impregnated with gelatine to confer zero porosity was compared to a standard knitted Dacron graft. The accumulation of platelets was assessed by reinfusion of 111In labelled platelets and imaging with a scintillation camera. The accumulation of platelets was significantly higher on the sealed grafts at the beginning of the experiments but a steady-state was rapidly achieved and no differences was observed regarding the patency.