Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Errors In Hypothesis Tests01:14

Errors In Hypothesis Tests

5.8K
When performing a hypothesis test, there are four possible outcomes depending on the actual truth (or falseness) of the null hypothesis and the decision to reject or not.
5.8K
Accuracy and Errors in Hypothesis Testing01:13

Accuracy and Errors in Hypothesis Testing

557
Hypothesis testing is a fundamental statistical tool that begins with the assumption that the null hypothesis H0 is true. During this process, two types of errors can occur: Type I and Type II. A Type I error refers to the incorrect rejection of a true null hypothesis, while a Type II error involves the failure to reject a false null hypothesis.
In hypothesis testing, the probability of making a Type I error, denoted as α, is commonly set at 0.05. This significance level indicates a 5%...
557
P-value01:10

P-value

8.5K
P-value is one of the most crucial concepts in statistics.
P-value stands for the probability value.  P-value is the probability that, if the null hypothesis is true, the results from another randomly selected sample will be as extreme or more extreme as the results obtained from the given sample.
A large P-value calculated from the data indicates to  not reject the null hypothesis. But a higher P-value does not mean that the null hypothesis is true. The smaller the P-value, the more...
8.5K
Significance Testing: Overview01:04

Significance Testing: Overview

11.5K
Significance testing is a set of statistical methods used to test whether a claim about a parameter is valid. In analytical chemistry, significance testing is used primarily to determine whether the difference between two values comes from determinate or random errors. The effect of a particular change in the measurement protocol, analyst, or sample itself can cause a deviation from the expected result. In the case of a suspected deviation/outlier, we need to be able to confirm mathematically...
11.5K
Bonferroni Test01:10

Bonferroni Test

3.3K
The Bonferroni test is a statistical test named after Carlo Emilio Bonferroni, an Italian mathematician best known for Bonferroni inequalities. This statistical test is a type of multiple comparison test to determine which means are different than the rest. Bonferroni test can minimize the Type 1 error by reducing the significance level alpha, which otherwise increases with sample pairs.
The means of different samples are first paired in all possible combinations.
The null hypothesis of the...
3.3K
Sign Test for Matched Pairs01:17

Sign Test for Matched Pairs

378
The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in...
378

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Resistant Hypertension Variants Link to Hyperaldosteronism and Potassium Levels.

Hypertension (Dallas, Tex. : 1979)·2026
Same author

Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms.

Gut·2026
Same author

Sustained Reduction in Cardiopulmonary Fitness in Long COVID: A Report from the RECOVER-adult Cohort Study.

JACC. Advances·2026
Same author

External validation of cough-based algorithms for pulmonary tuberculosis screening from the CODA TB DREAM challenge using cough data from Peru.

Scientific reports·2026
Same author

Dynamics of genetic and somatic trade-offs in ageing and mortality.

Nature·2026
Same author

A meta-analysis identifies driver genes and characterizes the molecular epidemiology of colorectal cancer.

Scientific reports·2026

Related Experiment Video

Updated: Jan 13, 2026

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
13:20

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance

Published on: December 5, 2025

611

"Bias toward the null" means reduced power

Solveig K Sieberts, Karl W Broman, Daniel F Gudbjartsson

    American Journal of Human Genetics
    |September 1, 2004
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget
    05:57

    Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget

    Published on: November 20, 2018

    58.6K
    Making Record-efficiency SnS Solar Cells by Thermal Evaporation and Atomic Layer Deposition
    14:01

    Making Record-efficiency SnS Solar Cells by Thermal Evaporation and Atomic Layer Deposition

    Published on: May 22, 2015

    43.3K

    Related Experiment Videos

    Last Updated: Jan 13, 2026

    Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
    13:20

    Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance

    Published on: December 5, 2025

    611
    Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget
    05:57

    Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget

    Published on: November 20, 2018

    58.6K
    Making Record-efficiency SnS Solar Cells by Thermal Evaporation and Atomic Layer Deposition
    14:01

    Making Record-efficiency SnS Solar Cells by Thermal Evaporation and Atomic Layer Deposition

    Published on: May 22, 2015

    43.3K