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Effects of protein kinase C on M-phase promoting factor in early development of fertilized mouse eggs

Bing-zhi Yu1, Jie Zheng, Ai-ming Yu

  • 1Department of Biochemistry, China Medical University, Shenyang, 110001, People's Republic of China. ybzbiochem@yeah.net

Cell Biochemistry and Function
|September 1, 2004
PubMed

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M-Cdk Drives Transition Into Mitosis02:15

M-Cdk Drives Transition Into Mitosis

Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...