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[Osteonecrosis in HIV-infected patients]
Edgardo G Bottaro1, Raúl H Figueroa, Pablo G Scapellato
1Grupo de Infectología, Hospital General de Agudos Donación F. Santojanni, Buenos Aires, Argentina. egbottaro@hotmail.com
Medicina
|September 2, 2004
Summary
Osteonecrosis (avascular necrosis) can affect HIV patients, potentially linked to HAART treatments and hyperlipidemia. Early diagnosis is crucial for managing bone death in HIV-infected individuals.
Area of Science:
- Orthopedics
- Infectious Diseases
- Hematology
Context:
- Osteonecrosis, or avascular necrosis, is bone death from compromised blood supply.
- Its incidence and cause in HIV patients are poorly understood.
- Potential factors include protease inhibitors, hyperlipidemia, and clotting issues.
Purpose:
- To investigate osteonecrosis in a cohort of HIV-infected patients.
- To identify potential risk factors and clinical presentations.
Summary:
- A series of 13 HIV patients with osteonecrosis presented with arthralgia.
- Common factors included steroid use, HAART-induced hyperlipidemia, smoking, and alcoholism.
- Anticardiolipin antibodies were found in 2 patients; most had AIDS on HAART.
Impact:
- Suggests considering osteonecrosis in HIV patients with joint pain.
- Recommends screening for HIV in patients diagnosed with osteonecrosis.