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Published on: July 29, 2022
[Purulent pericarditis with pericardial tamponade caused by Streptococcus agalactiae and Salmonella enterica no
Lourdes Arruvito1, Marcos G Ber, José A Martínez Martínez
1Departamento de Medicina Interna, Hospital de Clínicas José de San Martín, Universidad de Buenos Aires, Argentina. lourarruvito@hotmail.com
Abstract:
Purulent pericarditis (PP) is an uncommon condition with high mortality. In the preantibiotic period, Staphyloccocus aureus and Streptococcus pneumoniae were the most common etiologic agents. We describe the case of a 75-year old man with septic shock, PP and cardiac tamponade caused by Streptococcus agalactiae and Salmonella enterica no-typhi. To our knowledge this association of pathogenic organisms has not been previously reported in the literature. The pathogenesis is here reviewed, and in our patient presumably, purulent pericarditis occurred via hematogeneus spread undergoing upper gastrointestinal endoscopy. The patient's course was complicated and he died on 34th hospital day. After this case report it is considered that differential etiologic diagnosis of PP should include these agents, especially in immunodepressed patients with predisposing factors.
Insights
Purulent pericarditis (PP) is a rare, fatal condition. A case report highlights Streptococcus agalactiae and Salmonella enterica non-typhi as unusual causes, emphasizing the need for broader diagnostic considerations in at-risk patients.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Purulent pericarditis (PP) is an uncommon cardiac condition associated with high mortality rates.
- Historically, Staphylococcus aureus and Streptococcus pneumoniae were the primary causative agents of PP.
Observation:
- This report details a unique case of a 75-year-old male experiencing septic shock, purulent pericarditis, and cardiac tamponade.
- The patient presented with a concurrent infection by Streptococcus agalactiae and Salmonella enterica non-typhi, an association not previously documented.
Findings:
- The likely route of infection was hematogenous spread, potentially linked to an upper gastrointestinal endoscopy procedure.
- Despite medical intervention, the patient's condition was complicated, leading to death on the 34th hospital day.
Implications:
- The findings suggest that Streptococcus agalactiae and Salmonella enterica non-typhi should be considered in the differential diagnosis of purulent pericarditis.
- This is particularly relevant for immunocompromised individuals or those with predisposing factors, broadening the etiological scope for PP.
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