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Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
Published on: May 10, 2024
[Proteins of blood plasma in patients with pancreonecrosis]
Abstract:
Dynamics of effective and general concentration of albumins and middle-size molecules in blood plasma of patients with severe pancreonecrosis is described. Significant differences of these data in operated and non-operated patients are revealed. A negative correlation between severity of pancreatic necrosis and concentrations of albumins, and a direct correlation between necrotic lesion and concentration of middle-size molecules in blood plasma were demonstrated. The above parameters are important for assessment of treatment efficacy, prognosis of postoperative complications and determination of indications to sanated relaparotomies in patients with pancreonecrosis.
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Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
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Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
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