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Updated: Aug 22, 2026

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
[Sigmental right ventricular contractile function in patients with ischemic heart disease]
N S Buslenko1, Iu I Buziashvili, I V Koksheneva
1A. N. Bakulev Research Center for Cardiovascular Surgery; Rublevskoye sh., 135, 121552 Moscow, Russia.
Insights
Dobutamine stress echocardiography revealed right ventricular dysfunction in ischemic heart disease patients. Stress doses of dobutamine induced ischemic changes, highlighting reversible myocardial dysfunction and scar tissue.
Area of Science:
- Cardiology
- Echocardiography
- Myocardial Function
Background:
- Ischemic heart disease often involves coronary artery lesions.
- Right ventricular function assessment is crucial in managing cardiac conditions.
Purpose of the Study:
- To evaluate segmental right ventricular function using dobutamine stress echocardiography.
- To identify patterns of right ventricular dysfunction in ischemic heart disease.
Main Methods:
- 101 patients with ischemic heart disease underwent dobutamine stress echocardiography.
- Segmental right ventricular wall motion was analyzed at rest and during dobutamine infusion.
- Wall motion score index and asynergic segments were quantified.
Main Results:
- At baseline, 34% of segments were asynergic; this decreased to 6% with low-dose dobutamine.
- High-dose dobutamine induced ischemic changes, increasing asynergic segments to 53% and affecting 90% of patients.
- Abnormalities included reversible dysfunction (28%), scar (6%), and ischemic risk zones (47%).
Conclusions:
- Dobutamine stress echocardiography effectively assesses segmental right ventricular function.
- Right ventricular dysfunction in ischemic heart disease is often reversible and linked to coronary artery involvement.
Abstract:
Segmental right ventricular function was assessed by dobutamine stress echocardiography in 101 patients with ischemic heart disease and multiple coronary artery lesions. At rest local wall motion abnormalities were found in 69% of patients. Overall 505 segments of the right ventricle were analyzed (5 per patient). At baseline 34% of segments were asynergic (31% - hypokinetic and 3% akinetic), right ventricular wall motion score index was 1.38+/-0.04. Low dose dobutamine infusion resulted in decrease of portion of asynergic segments (to 6%) and lowering of wall motion score index (to 1.09+/-0.02, p<0.001 vs baseline). The use of stress doses of dobutamine was associated with appearance of ischemic changes of the right ventricle accompanied with typical anginal attacks and ST-segment depressions; increases of portions of asynergic segments (up to 53% including 43% hypokinetic and 10% akinetic), and of patients with abnormalities of local contractility (up to 90%); rise of wall motion score index (up to 1.64+/-0.05, p<0.001 vs low dose dobutamine). Segmental right ventricular wall motion abnormalities reflected mostly reversible myocardial dysfunction (hibernating myocardium was revealed in 28, scar - in 6, and zone at risk of ischemia - in 47% of all segments). Right ventricular myocardial dysfunction developed in patients with predominant involvement of the right coronary artery or anterior interventricular branch.
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