Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quorum sensing and signal interference: diverse implications.

Lian-Hui Zhang1, Yi-Hu Dong

  • 1Institute of Molecular and Cell Biology, 30 Medical Drive, Singapore 117609. lianhui@imcb.a-star.edu.sg

Molecular Microbiology
|September 3, 2004
PubMed
Summary

Quorum sensing (QS) controls microbial communities and can be disrupted by signal interference. This approach shows promise for controlling infections and biofilms, with implications for host-pathogen interactions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional Characterisation of the Quorum-Sensing Regulator ExpR<sub>Ecz</sub> in Modulation of Dickeya oryzae Motility and Virulence.

Molecular plant pathology·2026
Same author

Cinnamic acid-hordenine hybrid derivatives as T3SS inhibitors against Dickeya spp. for soft rot disease control.

Pest management science·2026
Same author

Dual-functional quorum sensing signal synthases DspII and DspI coordinate virulence switch in Pseudomonas aeruginosa.

Nature communications·2026
Same author

<i>Cis</i>-2-decenoic acid modulates <i>Pseudomonas aeruginosa</i> virulence through a noncanonical transcriptional regulator.

mLife·2026
Same author

Quaternary ammonium cationic surfactants target Vfm quorum sensing to suppress the virulence of rice pathogen Dickeya oryzae.

Pesticide biochemistry and physiology·2025
Same author

Design, synthesis, and biological evaluation of disulfides based on garlic extract against rice bacterial leaf blight caused by Pantoea ananatis.

Pest management science·2025

Area of Science:

  • Microbiology
  • Biochemistry
  • Molecular Biology

Background:

  • Quorum sensing (QS) is a cell-to-cell communication mechanism regulating bacterial behavior.
  • QS controls crucial microbiological functions in medical, agricultural, and industrial settings.
  • Understanding QS is key to managing microbial communities.

Purpose of the Study:

  • To explore microbial QS signals and interference mechanisms.
  • To evaluate QS interference as a strategy against microbial infections and biofilms.
  • To investigate the role of QS in host-pathogen interactions and microbial ecology.

Main Methods:

  • Identification of microbial QS signals and their associated pathways.
  • Discovery and characterization of enzymatic and non-enzymatic signal interference strategies.

Related Experiment Videos

  • Analysis of QS mechanisms in both microorganisms and host organisms.

    • Main Results:

    • Numerous QS signal interference mechanisms have been identified.
    • These interference mechanisms show potential for controlling microbial infections and biofilm formation.
    • QS and its interference mechanisms are relevant in host-pathogen interactions and microbial ecology.

    Conclusions:

    • QS signal interference represents a promising therapeutic and control strategy.
    • Further investigation into QS and interference mechanisms can expand microbiological research.
    • QS plays a significant role in microbial ecology and host-pathogen dynamics.