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Membrane targeting: glued by a lipid to the ER
1Institute of Biochemistry, Technical University Graz, Petersgasse 12/2, A-8010 Graz, Austria. guenther.daum@tugraz.at
Current Biology : CB
|September 3, 2004
Abstract:
Opi1p, a transcription regulator of phospholipid metabolism in budding yeast, is retained in the endoplasmic reticulum by association with Scs2p. New research shows that binding of phosphatidic acid to Opi1p is a prerequisite for this targeting.