Intussusception in early childhood: a cohort study of 1.7 million children

Thea Kølsen Fischer1, Kristine Bihrmann, Michael Perch

  • 1Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS-A34, Atlanta, GA 30333, USA. thf7@cdc.gov

Pediatrics
|September 3, 2004
PubMed

Insights

Intussusception incidence in Danish children remained stable until 1990, then significantly decreased by 55% through 2001. This decline was most notable in infants aged 3 to 5 months, indicating a positive public health trend.

Area of Science:

  • Pediatric epidemiology
  • Gastrointestinal health

Background:

  • Intussusception is a serious gastrointestinal condition in infants and young children.
  • Understanding incidence trends is crucial for public health monitoring and resource allocation.

Purpose of the Study:

  • To analyze the incidence and temporal trends of intussusception in Danish children.
  • To investigate changes in intussusception rates between 1980 and 2001.

Main Methods:

  • Population-based cohort study in Denmark (1980-2001).
  • Involved 1.67 million children younger than 5 years.
  • Utilized the Danish National Patient Registry to identify cases and calculate age-specific incidence rates.

Main Results:

  • 1814 cases of intussusception were reported.
  • Incidence was stable from 1980-1990.
  • A 55% decrease in incidence was observed from 1990-2001, most significant in 3-5 month olds.

Conclusions:

  • Intussusception incidence in Danish children declined significantly in the 1990s.
  • The reduction was particularly pronounced in infants aged 3 to 5 months.
Abstract