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Related Experiment Videos

Screening for post-miscarriage psychiatric morbidity.

Ingrid H Lok1, Dominic T S Lee, Shing-Kai Yip

  • 1Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. ingridlok@cuhk.edu.hk

American Journal of Obstetrics and Gynecology
|September 3, 2004
PubMed
Summary

The 12-item General Health Questionnaire (GHQ-12) effectively screens for psychiatric issues following miscarriage. With a cutoff score of 4, it shows high accuracy in identifying mental health conditions in women post-miscarriage.

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Area of Science:

  • Psychiatry
  • Women's Health
  • Mental Health Screening

Background:

  • Post-miscarriage psychiatric morbidity is a significant concern.
  • Effective screening tools are needed to identify at-risk individuals.
  • The 12-item General Health Questionnaire (GHQ-12) is a widely used screening instrument.

Purpose of the Study:

  • To evaluate the efficacy of the GHQ-12 in screening for psychiatric morbidity after miscarriage.
  • To determine the optimal cutoff score for the GHQ-12 in this population.

Main Methods:

  • A prospective cohort study involving 222 patients post-miscarriage.
  • Administration of the GHQ-12 six weeks after miscarriage.
  • Psychiatric diagnosis using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-III-R (SCID-III-R) by a psychiatrist.

Related Experiment Videos

  • Receiver operating characteristic (ROC) curve analysis to determine optimal cutoff and assess test characteristics.

    • Main Results:

    • Twenty-seven patients (12.2%) were identified as psychiatric cases.
    • The ROC curve analysis yielded an area under the curve of 0.93 (95% CI 0.87-0.99, P<.001).
    • An optimal GHQ-12 cutoff score of ≥4 demonstrated a sensitivity of 83%, specificity of 90%, positive predictive value of 50%, and negative predictive value of 98%.

    Conclusions:

    • The GHQ-12 is a valid and effective screening tool for detecting psychiatric morbidity in women following a miscarriage.
    • The recommended cutoff score of ≥4 provides a balance of sensitivity and specificity for screening.