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Published on: February 9, 2011
Intra-abdominal, retroperitoneal, and visceral abscesses in children
1Department of Pediatrics, Georgetown University School of Medicine, Washington, DC 20016, USA. ib6@georgetown.edu
Insights
This review covers pediatric intra-abdominal abscesses, detailing their causes, common bacteria, and treatment. Management involves drainage, surgery, and antibiotics targeting both aerobic and anaerobic microbes.
Area of Science:
- Pediatric Infectious Diseases
- Surgical Microbiology
Background:
- Intra-abdominal abscesses in children often arise from peritonitis, frequently secondary to appendicitis or necrotizing enterocolitis.
- Causes include intestinal defects from obstruction, infarction, or trauma, allowing enteric microorganisms to enter the peritoneal cavity.
Purpose of the Study:
- To review the microbiology, diagnosis, and management of pediatric intra-abdominal abscesses.
- To outline common pathogens and effective treatment strategies for these infections.
Main Methods:
- Literature review focusing on intra-abdominal abscesses in pediatric populations.
- Analysis of microbiological data, diagnostic approaches, and therapeutic interventions.
Main Results:
- Commonly identified aerobic bacteria include Escherichia coli, Staphylococcus aureus, and Enterococcus spp.
- Predominant anaerobic isolates are Bacteroides fragilis group, Peptostreptococcus spp., Fusobacterium spp., and Clostridium spp.
- Abscesses are often polymicrobial, involving both aerobic and anaerobic organisms.
Conclusions:
- Effective management of pediatric intra-abdominal abscesses requires a multi-modal approach.
- Treatment necessitates source control (drainage, surgery) and broad-spectrum antimicrobial therapy.
- Targeting both aerobic and anaerobic bacteria is crucial for successful outcomes.
Abstract:
This review describes the microbiology, diagnosis, and management of intra-abdominal abscesses (including subphrenic, hepatic, splenic, and retroperitoneal abscesses) in children. They often occur as a complication of local or generalized peritonitis, commonly secondary to appendicitis, necrotizing enterocolitis, pelvic inflammatory disease, and tubo-ovarian infection, surgery or trauma. The original infection generally occurs because of the entry of enteric microorganisms into the peritoneal cavity through a defect in the wall of the intestine or other viscus as a result of obstruction, infarction, or direct trauma. Mixed aerobic and anaerobic flora can be recovered from most abscesses. The predominant aerobic isolates are Escherichia coli, Staphylococcus aureus, and Enterococcus spp. and the main anaerobic bacteria are Bacteroides fragilis group Peptostreptococcus spp., Fusobacterium spp., and Clostridium spp. The treatment of intraabdominal abscesses includes drainage, surgical correction of pathology, and administration of antimicrobials effective against both aerobic and anaerobic microorganisms.
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