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Changing patterns in surgery for chronic renal artery occlusive diseases
C E Bredenberg1, L N Sampson, F S Ray
1Department of Surgery, Maine Medical Center, Portland 04102.
Insights
Surgical intervention for chronic renal artery occlusive disease primarily focused on renal function salvage due to advanced atherosclerosis. Most patients avoided long-term dialysis after these complex vascular reconstructions.
Area of Science:
- Vascular Surgery
- Nephrology
- Cardiovascular Disease
Background:
- Chronic renal artery occlusive diseases pose significant risks to kidney function.
- Atherosclerosis is a leading cause of renal artery stenosis, particularly in older populations.
- Surgical management has evolved due to advances in hypertension treatment and endovascular techniques.
Purpose of the Study:
- To analyze surgical outcomes for chronic renal artery occlusive diseases.
- To identify the primary indications and etiologies for surgical intervention.
- To evaluate the effectiveness of various reconstruction techniques in salvaging renal function.
Main Methods:
- Retrospective review of 66 patients (69 operations) between 1985 and 1990.
- Analysis of patient demographics, etiology of disease, surgical procedures, and outcomes.
- Categorization of reconstruction methods based on donor arteries (aorta, aortic graft, other abdominal arteries).
Main Results:
- Atherosclerosis accounted for 90% of cases, with generalized disease in 83%.
- Renal function salvage was the primary goal in 72% of operations.
- 86% of patients undergoing renal salvage avoided long-term dialysis; operative mortality was 3%.
Conclusions:
- Modern surgical management of renal artery occlusive disease addresses advanced atherosclerosis and prioritizes renal function preservation.
- Complex reconstructions, often avoiding the aorta, are necessary due to disease severity.
- Improved medical management has shifted surgical indications from hypertension control to renal salvage.
Abstract:
We report 66 patients undergoing 69 operations for chronic renal artery occlusive diseases operated on at two institutions between January 1985 and June 1990. Etiology was atherosclerosis in 59 patients (90%); fibromuscular disease in four (6%), and three children with nonfibromuscular disease stenosis (4%). Atherosclerosis was local in 10 and generalized in 49 (83% of all patients). Fifty operations (72%) were for salvage of renal function. Average serum creatinine was 2.3 mg/dl and was elevated in 46 patients (70%). Donor arteries for reconstruction were aorta 20 (29%), aortic graft 16 (23%), and other abdominal arteries 33 (48%). Twenty-one patients had concomitant vascular procedures including 16 aortic replacements. The two operative deaths (3%) followed aortic replacements. Three grafts (4%) occluded before discharge from the hospital. Eighty-six percent of patients undergoing renal salvage avoided long-term dialysis. In past decades fibromuscular disease and localized atherosclerosis were the most frequent renal artery occlusive diseases undergoing surgery, hypertension was the predominant indication, and the most frequent operation was aortorenal bypass. As a result of improved pharmacologic management of hypertension and the development of percutaneous transluminal dilation, most patients in this series had far advanced generalized atherosclerosis, and renal salvage was the most frequent indication for operation. As a consequence of the severity of the atherosclerosis, 48% of operations avoided the aorta, 23% replaced the aorta, and aortorenal bypass was used in only 29%.
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