[Protein hydrolysis by pepsin and trypsin at a varying pH]

The continuity of the pepsin and trysin action on the proteinic substrates with different pH was studied. A short-term incubation of protein with pepsin at high pH intensifies the tryptic effect on this protein, the initial rate of the protein hydrolysis then gains momentum and the possibility of its complete hydrolysis increases over the same period of time. With successive action of fibrin of the gastric and pancreatic secretions prinicipally the same relationship has been established.