Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The SSEA server for protein secondary structure alignment.

Paolo Fontana1, Eckart Bindewald, Stefano Toppo

  • 1Istituto Agrario di San Michele all'Adige, via E. Mach 1, 38010 S. Michele all'Adige (TN), Italy.

Bioinformatics (Oxford, England)
|September 7, 2004
PubMed
Summary

A new web server provides protein secondary structure alignments for pairwise comparisons and fold library searches. This tool aids in domain identification and novel fold discrimination using global and local alignment methods.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

On the state of protein function prediction: a report on the fourth CAFA challenge.

bioRxiv : the preprint server for biology·2026
Same author

The Impact of Clinical and Demographic Factors on High-Risk Patient Classification Frequencies by the EndoPredict Test: A Review and Single-Site Study.

Cancers·2026
Same author

Comparative Multi-Marker Environmental DNA Metabarcoding of Marine Metazoan Communities: Water vs. Sediment.

Molecular ecology resources·2026
Same author

A new cryptic species of <i>Chelidurella</i> Verhoeff, 1902 (Dermaptera, Forficulidae) from the Italian Alps: molecular evidence reveals hidden diversity in a high-altitude refugium.

ZooKeys·2026
Same author

Paired Duodenal and Salivary Microbiome Analysis in Pancreatic Cancer Without Duct Obstruction.

United European gastroenterology journal·2026
Same author

Protective Effects of Grapeseed Proanthocyanidins in Ulcerative Colitis: A Pilot Study Evaluating a Potential Therapeutic Strategy.

Journal of clinical medicine·2026

Area of Science:

  • Structural bioinformatics
  • Computational biology
  • Protein structure analysis

Background:

  • Protein secondary structure analysis is crucial for understanding protein function and evolution.
  • Existing methods for secondary structure alignment have limitations in scope and flexibility.

Purpose of the Study:

  • To develop and present a novel web server for computing protein secondary structure alignments.
  • To offer versatile alignment capabilities including pairwise comparisons and fold library searches.

Main Methods:

  • The web server implements algorithms for both global and local secondary structure element alignments.
  • It supports pairwise alignments and searching query structures against curated fold libraries (SCOP, PDB).

Main Results:

Related Experiment Videos

  • The server enables comprehensive secondary structure alignments, facilitating domain identification within query sequences.
  • It assists in the discrimination of novel protein folds by comparing against established libraries.

Conclusions:

  • The developed web server offers a valuable resource for researchers in structural bioinformatics and computational biology.
  • Its flexible alignment options enhance the analysis and understanding of protein structures and folds.