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Calcium phosphate bone cements for clinical applications. Part I: solution chemistry
E Fernández1, F J Gil, M P Ginebra
1Dpt Materials Science and Metallurgy, Universitat Politècnica de Catalunya, Avda. Diagonal 647, 08028-Barcelona, Spain.
Journal of Materials Science. Materials in Medicine
|September 7, 2004
Summary
Calcium phosphate cements are widely studied for bone repair due to their biocompatibility and hardening capabilities. Their setting involves chemical reactions and phase transformations at body temperature.
Area of Science:
- Biomaterials Science
- Surgical Innovation
- Crystallography
Background:
- Calcium phosphate cements (CPCs) are extensively researched for bone regeneration and surgical applications.
- Key properties include biocompatibility, bone void filling capacity, and controlled hardening.
- These attributes make CPCs highly desirable for various orthopedic and dental procedures.
Purpose of the Study:
- To review the fundamental properties and setting mechanisms of calcium phosphate cements.
- To highlight the significance of their biocompatibility and hardening characteristics.
- To underscore their broad applicability in surgical settings.
Main Methods:
- Literature review focusing on calcium phosphate cement research over the past decade.
- Analysis of the chemical reactions governing cement setting and hardening.
- Examination of crystalline phase transformations during material setting.
Main Results:
- Calcium phosphate cements demonstrate excellent biocompatibility.
- Their capacity to fill bone cavities effectively is a significant advantage.
- Controlled hardening through dissolution-precipitation reactions is a key feature.
Conclusions:
- Calcium phosphate cements possess desirable properties for surgical applications.
- The setting process involves complex chemical reactions and phase changes.
- Continued research is vital for optimizing CPCs in bone repair and augmentation.