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Hydroxypatite-polysaccharide granules for drug delivery
E Krylova1, A Ivanov, V Orlovski
1Scientific and Technology Center Spectrum RAS and RAES, Leninskij pr. 31, Moscow, 117907, Russia.
Journal of Materials Science. Materials in Medicine
|September 7, 2004
Abstract:
The formation of hydroxyapatite by co-precipitation from sodium alginate and sodium carboxymethylcellulose aqueous solutions with the use of dibasic calcium phosphate dihydrate and calcium hydroxide as starting reagents is studied. A technique to prepare the hydroxyapatite/polysaccharide (micro)granules is developed. An introduction of an antimicrobial Biocide 1 agent in proper amount into the granules is provided, and the behavior of the granules is evaluated.