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Published on: August 15, 2016
Endothelial cell adhesion on bioerodable polymers
A Ahluwalia1, G Basta, F Chiellini
1Interdepartmental Research Center E. Piaggio, University of Pisa, Via Diotisalvi 2, Pisa 56126, Italy. arti@piaggio.ccii.unipi.it
Abstract:
This paper presents the results of a preliminary screening of a new class of bioerodable polymers, partial esters of alternating copolymers of maleic anhydride and mono-methoxyoligoethyleneglycol vinyl ethers (PAM) for use in engineered vascular tissue. Different initial concentrations of PAM and human serum albumin (HSA) were spin-coated onto glass substrates and the surface properties of the resulting films and their relationship to endothelial cell adhesion was examined. An optimum PAM/HSA blend for use as the cell contact surface of a bioerodable scaffold was identified.
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