Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 21, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
05:41

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

Hydroxyapatite spheres with controlled porosity for eye ball prosthesis: processing and characterization.

E Rivera-Muñoz1, J R Díaz, J Rogelio Rodríguez

  • 1Instituto de Física, Universidad Nacional Autónoma de México, A.P. 1-1010, Querétaro, Querétaro 76000, Mexico.

Journal of Materials Science. Materials in Medicine
|September 7, 2004
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Solid-State Carbon-13 CP-MAS NMR Analysis of Carboxymethyl Cellulose Sodium Salt (CMC) Derived From Cotton and Other Sources.

Magnetic resonance in chemistry : MRC·2025
Same author

Novel non-thermoluminescent CaSO<sub>4</sub>:Dy dosimeters.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2024
Same author

Factors affecting N-acetyl-β-D-glucosaminidase as an indicator for mastitis detection in dairy sheep.

Animal : an international journal of animal bioscience·2024
Same author

Simulation of alpha particle emitted by <sup>222</sup>Rn from natural spring water in Puebla, México.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2022
Same author

Effect of the pulsation type (alternate or simultaneous) on milk yield and health status of the mammary gland of Murciano-Granadina goats.

Journal of dairy science·2019
Same author

Relationship of mammary gland health status and other noninfectious factors with electrical conductivity of milk in Manchega ewes.

Journal of dairy science·2016

This study aimed to develop hydroxyapatite spheres with controlled porosity for use in eye prostheses. Using a modified gelcasting method, the researchers produced spheres approximately 2.2 cm in diameter with pore sizes ranging from 10 to 40 micrometers. The material composition was confirmed using X-ray and infrared spectroscopy, while surface morphology and porosity were evaluated with scanning electron microscopy and BET measurements. The results suggest that the modified method successfully controls porosity, which could improve the performance of prosthetic devices. The authors propose that these spheres may serve as suitable candidates for eye prostheses, offering better integration and mechanical properties.

Area of Science:

  • Bioceramics in biomedical engineering
  • Material processing for prosthetic devices

Background:

Current research in biomedical engineering aims to improve the design of prosthetic devices to better mimic natural tissues. Prior studies have explored the use of hydroxyapatite as a biocompatible material for implants. However, achieving consistent porosity in ceramic structures remains a challenge. Researchers have demonstrated that porosity influences mechanical properties and integration with surrounding tissues. Despite these findings, few studies have focused on controlled porosity in hydroxyapatite spheres specifically for eye prostheses. This gap motivated the investigation of a modified gelcasting method. The goal is to produce spheres with uniform pore size distribution. The study addresses the lack of reproducible methods for ceramic prosthesis fabrication.

Purpose Of The Study:

The study aimed to develop a method for creating hydroxyapatite spheres with controlled porosity for use in eye prostheses. The specific problem is the difficulty in achieving consistent pore size and distribution in ceramic prostheses. The motivation stems from the need for improved integration and mechanical performance in prosthetic devices. The researchers sought to modify the gelcasting process to address these limitations. By controlling porosity, the material could better support tissue integration. The study also aimed to evaluate the effectiveness of the modified method. The results could inform future developments in biocompatible prosthetic materials. This work contributes to the field of biomedical ceramics.

Keywords:
hydroxyapatiteporous ceramicsprosthetic materialsbiomedical engineering

Frequently Asked Questions

The study produced hydroxyapatite spheres with controlled porosity (10–40 microm) using a modified gelcasting method.

Porosity was assessed using scanning electron microscopy (SEM) and BET surface area measurements.

Uniform pore size (10–40 microm) is proposed to enhance tissue integration and mechanical performance in prosthetic applications.

X-ray powder diffractometry (XRD) and Fourier transform infrared spectroscopy (FTIR) were used to identify phases.

More Related Videos

Fabricating Highly Open Porous Microspheres (HOPMs) via Microfluidic Technology
05:21

Fabricating Highly Open Porous Microspheres (HOPMs) via Microfluidic Technology

Published on: May 16, 2022

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
07:14

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

Related Experiment Videos

Last Updated: Jul 21, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
05:41

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

Fabricating Highly Open Porous Microspheres (HOPMs) via Microfluidic Technology
05:21

Fabricating Highly Open Porous Microspheres (HOPMs) via Microfluidic Technology

Published on: May 16, 2022

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
07:14

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

Main Methods:

The researchers employed a modified gelcasting method to fabricate hydroxyapatite spheres. The process involved preparing a ceramic slurry and casting it into spherical molds. The spheres were approximately 2.2 cm in diameter. To assess the material composition, X-ray powder diffractometry (XRD) was used before and after processing. Fourier transform infrared spectroscopy (FTIR) was applied to identify any phase changes. Scanning electron microscopy (SEM) was utilized to examine surface morphology and pore structure. BET surface area measurements were conducted to quantify porosity. These analytical techniques provided a comprehensive characterization of the spheres.

Main Results:

The fabricated spheres exhibited a diameter of 2.2 cm with a pore size distribution ranging from 10 to 40 micrometers. XRD analysis confirmed the presence of hydroxyapatite phases before and after processing. FTIR results indicated minimal structural changes during the gelcasting process. SEM images revealed a relatively homogeneous pore distribution across the spheres. The surface morphology showed no significant defects or irregularities. BET measurements provided quantitative data on surface area and porosity. The results suggest that the modified gelcasting method successfully controls porosity. These findings support the potential use of the spheres in biomedical applications.

Conclusions:

The study demonstrated that a modified gelcasting method can produce hydroxyapatite spheres with controlled porosity. The results suggest that the method effectively maintains phase stability and pore size distribution. The researchers propose that the spheres could serve as suitable candidates for eye prostheses. The findings indicate that the material's properties align with requirements for biomedical implants. The study highlights the importance of process optimization in ceramic fabrication. The authors suggest that further work is needed to evaluate long-term performance. The results provide a foundation for future research in biocompatible materials. This work contributes to the development of advanced prosthetic devices.

The spheres were approximately 2.2 cm in diameter with consistent pore size distribution.

The authors suggest the method could lead to improved biocompatible prosthetic materials for eye implantation.