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Updated: Aug 18, 2026

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration
Published on: June 16, 2015
Osseous regeneration in the presence of oxidized cellulose and collagen
G J Dias1, P V Peplow, F Teixeira
1Department of Anatomy and Structural Biology, University of Otago, P.O. Box 913, Dunedin, New Zealand. george.dias@stonebow.otago.ac.nz
Abstract:
Oxidized cellulose and collagen are two absorbable hemostatic scaffolding materials that are used widely in surgery. A histomorphological study was undertaken to determine the tissue response and extent of healing brought about by intraosseously implanting these two materials in the femur and tibia of sheep. There was no major difference in the rate of repair of the bone defects brought about by these two materials, with the bone defects being completely repaired by lamellar bone at 6-8 weeks. Therefore, our results suggest that, in most instances where collagen is presently used in surgical applications, it could be substituted by oxidized cellulose.
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