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The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits
Published on: August 20, 2014
Radiation enhanced modification of HDPE for medical applications
1National Metal and Materials Technology Center, National Science and Technology Development Agency, Ministry of Science and Technology, 114 Paholyothin Road, Klong 1, Klongluang, Pathumthani 12120, Thailand.
Abstract:
Comparison of gamma irradiation induced change in properties in terms of thermal and mechanical properties between two grades of HDPE and UHMWPE was carried out. It was found that the responses to irradiation of two grades of HDPE investigated were close whereas a difference in response was found between HDPE and UHMWPE. The irradiation dose that caused the lowest wear and highest hardness for UHMWPE was 500 kGy. When irradiation dose was above 500 kGy, no significant changes in wear and hardness properties were observed. The irradiation dose for HDPE, both 2208J and 7000F, that caused the wear resistance and hardness comparable to irradiated UHMWPE at 500 kGy was 1000 kGy. In addition, the dose of 750 kGy was needed for HDPE to achieve the similar level of wear resistance as non-irradiated UHMWPE.
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