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Updated: Aug 22, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Ophthalmic artery occlusion secondary to radiation-induced vasculopathy
Rita Singh1, Jonathan D Trobe, James A Hayman
1Department of Ophthalmology, Kellogg Eye Center, University of Michigan Medical Center, 1000 Wall Street, Ann Arbor, MI 48105, USA.
Abstract:
A 35-year-old man with neurofibromatosis type 1 (NF1) had a left ophthalmic artery occlusion that caused no light perception OS 28 years after having been treated with external beam radiation therapy for a presumed glioma of the right optic nerve and chiasm. Clinical and imaging findings were consistent with radiation-induced cerebral vasculopathy. This ophthalmic complication has never been reported, despite the common occurrence of severe carotid-ophthalmic artery junction stenosis after radiation in NF1 patients. Even though modern radiation techniques limit collateral damage, this modality should be used with discretion in NF1 patients, given the vulnerability of their immature cerebral vasculature to radiation.
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