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[Chronic enterocolopathies and SAPHO syndrome. 8 cases]
M F Kahn1, J P Bouchon, A M Chamot
1Service de Rhumatologie, Hôpital Bichat, Université Paris.
Revue Du Rhumatisme Et Des Maladies Osteo-Articulaires
|February 1, 1992
Summary
SAPHO syndrome, a bone disorder, was studied in 61 patients. Researchers observed 8 cases of inflammatory bowel disease, suggesting a link between SAPHO syndrome and spondylarthropathies.
Area of Science:
- Rheumatology
- Gastroenterology
- Dermatology
Context:
- SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis) syndrome is a rare autoinflammatory disorder.
- Understanding the comorbidities and associations of SAPHO syndrome is crucial for comprehensive patient management.
Purpose:
- To investigate the prevalence of chronic inflammatory bowel diseases (IBD) in patients diagnosed with SAPHO syndrome.
- To explore potential associations between SAPHO syndrome and other conditions, particularly spondylarthropathies.
Summary:
- A cohort of 61 patients with bone-involved SAPHO syndrome was analyzed.
- Eight cases (13.1%) exhibited chronic inflammatory bowel diseases: 6 Crohn's disease and 2 ulcerative colitis.
- Associated conditions included sacro-iliitis (5 patients), palmoplantar pustulosis (4), psoriasis (3), and acne (1).
- Four patients tested positive for the HLA B27 antigen.
Impact:
- Findings suggest a potential link between SAPHO syndrome and spondylarthropathies, warranting further investigation.
- Highlights the importance of screening for IBD in SAPHO syndrome patients.
- Contributes to the classification and understanding of SAPHO syndrome within the spectrum of autoinflammatory and spondyloarthritic conditions.
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