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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Prevention of percutaneous endoscopic gastrostomy site infections caused by methicillin-resistant Staphylococcus

G Gopal Rao1, M Osman, L Johnson

  • 1Department of Infection Control, University Hospital Lewisham, London SE13 6LH, UK. gopal.rao@uhl.nhs.uk

The Journal of Hospital Infection
|September 8, 2004
PubMed

Insights

A strategy combining screening, skin decontamination, and glycopeptide prophylaxis effectively prevented percutaneous endoscopic gastrostomy (PEG) site infections, including those caused by MRSA.

Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Surgical Site Infections

Background:

  • Percutaneous endoscopic gastrostomy (PEG) is crucial for enteral nutrition in patients with swallowing difficulties.
  • Peristomal wound infection is a common complication following PEG procedures.
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent cause of these infections in endemic settings.

Purpose of the Study:

  • To evaluate the efficacy of a comprehensive strategy for preventing PEG-site infections.
  • To assess the role of screening, skin decontamination, and glycopeptide prophylaxis in MRSA prevention.

Main Methods:

  • A prospective study involving three groups of patients undergoing PEG.
  • Group A: Screening, skin decontamination, and glycopeptide prophylaxis.
  • Group B: Decontamination alone; Group C: Glycopeptide prophylaxis alone.

Main Results:

  • No PEG-site infections occurred in Group A within one month; two MRSA infections occurred later.
  • One MRSA infection occurred in Group B within the surveillance period; another occurred later.
  • No infections were observed in Group C.

Conclusions:

  • The combined strategy of screening, decontamination, and glycopeptide prophylaxis appears effective in preventing PEG-site infections, particularly MRSA.
  • Further research is warranted to validate these findings in larger trials.

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