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Published on: December 17, 2010
Traumatic partial hypopituitarism in a cat
1Davies White Veterinary Specialists, Manor Farm Business Park, Higham Gobion, Hertfordshire.
The Journal of Small Animal Practice
|September 9, 2004
Summary
Traumatic hypopituitarism in a cat caused by head trauma led to central diabetes insipidus. Treatment with antidiuretic hormone successfully resolved excessive thirst and urination.
Area of Science:
- Veterinary Neurology
- Endocrinology
Background:
- Traumatic brain injury can disrupt pituitary gland function, leading to hypopituitarism.
- Hypopituitarism in animals presents with a range of clinical signs depending on the affected hormones.
Observation:
- An 11-month-old cat exhibited polydipsia, polyuria, and lethargy following head trauma.
- Neurological deficits included mydriasis and impaired limb reflexes and proprioception.
- Laboratory results indicated hormonal deficiencies (cortisol, thyroxine, TSH, IGF-1) and isosthenuria.
Findings:
- A diagnosis of traumatic hypopituitarism was confirmed.
- Central diabetes insipidus was identified via a water deprivation test.
- Hormonal replacement therapy with synthetic antidiuretic hormone was initiated.
Implications:
- This case highlights the potential for head trauma to cause hypopituitarism in cats.
- Early diagnosis and hormonal management are crucial for improving outcomes in traumatic hypopituitarism.
- Further research into the long-term effects of traumatic hypopituitarism in felines is warranted.

