Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Review article: problematic proctitis and distal colitis.

P Gionchetti1, F Rizzello, C Morselli

  • 1Department of Internal Medicine, University of Bologna, Italy. paolo@med.unibo.it

Alimentary Pharmacology & Therapeutics
|September 9, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of gunshot wound to the lumbosacral spine in a 17-year-old girl without neurological impairment.

Journal of biological regulators and homeostatic agents·2020
Same author

Video-assisted anterior retroperitoneal approach to the lumbar spine. A minimally invasive technique improved by the use of an endoscopic camera to treat lumbar spinal diseases. Consideration over 269 patients.

Journal of biological regulators and homeostatic agents·2020
Same author

Use of lordotic cages in L5-S1 Anterior Lumbar Interbody Fusion (ALIF) procedures

Journal of biological regulators and homeostatic agents·2020
Same author

Strictureplasty for Crohn's disease of the small bowel in the biologic era: long-term outcomes and risk factors for recurrence.

Techniques in coloproctology·2020
Same author

Arthrogenic human synovial cysts: immunohistochemical profile of interleukin-1beta, interleukin-6, tumour necrosis factor-alpha.

Folia morphologica·2020
Same author

Influence of male human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection on the reproductive outcomes in serodiscordant couples: a case-control study.

Andrology·2019
Same journal

Letter: Interpreting P-CAB Superiority for Antithrombotic Gastroprotection Beyond Acid Suppression. Authors' Reply.

Alimentary pharmacology & therapeutics·2026
Same journal

Letter: Low FODMAP Therapy in Paediatric Irritable Bowel Syndrome: Balancing Efficacy, Expectancy and Safety.

Alimentary pharmacology & therapeutics·2026
Same journal

Letter: Assessing Pruritus Efficacy With Peroxisome Proliferator-Activated Receptor Agonists in Primary Biliary Cholangitis Must Include Grading the Strength of Trial Evidence.

Alimentary pharmacology & therapeutics·2026
Same journal

Review Article: Advances in the Diagnosis of Dysplasia in Barrett's Oesophagus.

Alimentary pharmacology & therapeutics·2026
Same journal

Eosinophilic Oesophagitis Beyond the Oesophagus: High Prevalence of Chronic Rhinosinusitis-Type Symptoms and Their Impact on Symptom Severity in Swiss EoE Cohort Study Patients.

Alimentary pharmacology & therapeutics·2026
Same journal

Natural History of Recurrent Acute Pancreatitis: Implications for Interventional Trial Design.

Alimentary pharmacology & therapeutics·2026
See all related articles

Topical aminosalicylate therapy is effective for most ulcerative colitis patients with distal inflammation. Formulation choice depends on disease extent and patient preference for optimal treatment outcomes.

Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • Ulcerative colitis (UC) often involves distal colonic inflammation, making topical treatments viable for many patients.
  • Topical therapies deliver medication directly to inflamed sites, minimizing systemic absorption and side effects.

Purpose of the Study:

  • To review current therapeutic strategies for ulcerative colitis, emphasizing topical treatments.
  • To guide the selection of appropriate formulations based on disease extent and patient factors.

Main Methods:

  • Review of aminosalicylate and glucocorticoid therapies for ulcerative colitis.
  • Discussion of alternative treatments and factors influencing therapeutic response.

Main Results:

  • Topical aminosalicylates are highly effective when reaching the disease's upper extent.

Related Experiment Videos

  • Combination therapies (oral/topical) and newer glucocorticoids offer options for refractory cases.
  • Intravenous steroids and other alternative treatments exist for severe or refractory disease.

    • Conclusions:

    • Treatment selection for ulcerative colitis should consider disease location, patient preference, and response to prior therapies.
    • Factors like pathogens, IBS, and adherence can impact treatment success, potentially necessitating colectomy in rare cases.