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Local infections after above-knee prosthetic femoropopliteal bypass for intermittent claudication
Gustav Pedersen1, Elin Laxdal, Malgorzata Hagala
1Department of Surgery, Haukeland University Hospital, Bergen, Norway. gustav.pedersen@helse-bergen.no
Insights
Prosthetic graft infections after treating intermittent claudication are common. A selective, individualized approach to managing infected femoropopliteal prostheses, considering clinical presentation and bacteria, is recommended.
Area of Science:
- Vascular Surgery
- Infectious Disease Management
Background:
- Prosthetic graft use for intermittent claudication remains controversial.
- Graft infection is a serious complication of prosthetic bypass surgery.
- Managing prosthetic graft infections presents significant challenges.
Purpose of the Study:
- To analyze lymphatic and local infection complications after prosthetic bypass for intermittent claudication.
- To identify risk factors associated with graft infections.
- To evaluate treatment outcomes for infected grafts.
Main Methods:
- Retrospective study of 141 consecutive operations on 129 patients (1990-2001).
- Analysis of lymphatic complications, surgical site infections, and graft infections.
- Correlation of complications with preoperative risk factors, secondary procedures, and outcomes.
Main Results:
- High rates of lymph complications (18/141), surgical site infections (11/141), and graft infections (17/141) observed.
- 11 of 17 infected grafts were successfully treated without excision, with 6 healing with antibiotics alone.
- Postoperative lymph fistula significantly correlated with local infection risk; reoperative surgery increased graft infection risk.
Conclusions:
- The study highlights a high frequency of graft infections in femoropopliteal prostheses.
- A selective, individualized approach to managing infected prostheses is suggested.
- Conservative management strategies for surgical treatment of intermittent claudication are advocated.
Background:
The use of prosthetic grafts in the treatment of intermittent claudication is still a controversy. Prosthetic bypass for this usually benign condition may in some cases lead to a graft infection. This potentially disastrous complication is difficult to manage.
Methods:
One hundred forty-one consecutive operations done on 129 patients between January, 1990 and December, 2001 in a single university vascular unit have been studied. Lymphatic complications and local infections have been related to preoperative risk factors, complications, secondary procedures, and outcome.
Results:
During a mean follow-up period of 42 months, lymph complications occurred after 18 operations, surgical site infection after 11 procedures, and graft infection after 17 operations. Eleven infected grafts were treated successfully without graft excision. Six of these grafts healed with antibiotics only. The risk of developing a local infection was significantly correlated with postoperative lymph fistula. Reoperative surgery was associated with graft infection. Graft infection caused by Staphylococcus aureus always warranted surgery, either local revision or graft excision.
Conclusions:
The present series had a high frequency of graft infections. Our data suggest that a selective approach should be taken towards excision of infected femoropopliteal prostheses. The need for and extent of surgery should be individualized according to the clinical presentation of the graft infection and the type of bacteria involved. We advocate a conservative attitude towards surgical treatment of intermittent claudication.
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