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Published on: November 14, 2017
Hemoglobin levels and Alzheimer disease: an epidemiologic study in India
Rajesh S Pandav1, Vijay Chandra, Hiroko H Dodge
1Division of Geriatrics and Neuropsychiatry, Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA.
Objective:
Anemia is common in developing countries, where populations are aging rapidly. The authors explored the cross-sectional relationship between hemoglobin concentration and Alzheimer disease (AD) in a rural elderly sample in Ballabgarh, India.
Methods:
A clinical diagnostic evaluation for dementia and a hemoglobin estimation were performed in 605 persons selected by screening a larger community-based sample age 55+ years. Twenty-six participants met criteria for AD.
Results:
Hemoglobin was inversely associated with AD after adjustment for age, sex, and literacy.
Conclusion:
Low hemoglobin is associated with AD and should be investigated further as a modifiable risk factor.
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