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Related Experiment Videos

High oxidation rates from combined carbohydrates ingested during exercise.

Roy L P G Jentjens1, Juul Achten, Asker E Jeukendrup

  • 1Human Performance Laboratory, School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, United Kingdom.

Medicine and Science in Sports and Exercise
|September 9, 2004
PubMed
Summary

Ingesting a mixture of glucose, fructose, and sucrose during intense exercise significantly boosts carbohydrate (CHO) oxidation rates. This blend enhances exogenous CHO oxidation compared to glucose alone, aiding athletic performance.

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Area of Science:

  • Exercise Physiology
  • Nutritional Science
  • Sports Medicine

Background:

  • Single carbohydrate oxidation during exercise typically reaches up to 1 g/min.
  • Previous research indicates carbohydrate (CHO) mixtures can yield higher oxidation rates (approx. 1.3 g/min) than glucose alone.
  • Optimal fueling strategies are crucial for endurance performance.

Purpose of the Study:

  • To determine if a glucose, fructose, and sucrose mixture ingested at a high rate (2.4 g/min) increases exogenous CHO oxidation beyond 1.3 g/min.
  • To compare exogenous CHO oxidation rates between a mixed-carbohydrate solution and a glucose-only solution during prolonged cycling.
  • To assess the impact of the mixed-carbohydrate solution on endogenous CHO oxidation.

Main Methods:

  • Eight trained male cyclists performed three 150-minute cycling trials at 62% VO2max.

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  • Participants consumed either water, a glucose-only solution (2.4 g/min), or a glucose-fructose-sucrose mixture (2.4 g/min total).
  • Exogenous and endogenous carbohydrate oxidation rates were measured using isotope-labeled tracers.
  • Main Results:

    • Peak exogenous CHO oxidation rates reached 1.70 g/min in the mixed-carbohydrate trial, 44% higher than the glucose-only trial (1.18 g/min).
    • Endogenous CHO oxidation was significantly lower in the mixed-carbohydrate trial compared to the glucose-only trial.
    • The high ingestion rate of 2.4 g/min was well-tolerated.

    Conclusions:

    • Simultaneous ingestion of glucose, fructose, and sucrose at high rates (2.4 g/min) during cycling exercise maximizes exogenous CHO oxidation.
    • Peak exogenous CHO oxidation rates can exceed 1.7 g/min with this mixed-carbohydrate strategy.
    • This approach may spare endogenous CHO stores, potentially benefiting endurance performance.