Related Experiment Video
Updated: Aug 22, 2026

Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis
Published on: December 9, 2022
The synthesis of peptides and proteins containing non-natural amino acids
David R W Hodgson1, John M Sanderson
1Department of Chemistry, South Road, Durham, UKDH1 3LE, UK. d.r.w.hodgson@durham.ac.uk
Abstract:
Methods for the incorporation of non-natural amino acids into proteins have advanced significantly over recent years and in this tutorial review we aim to give a general overview of the area. These techniques offer the possibility of modulating the structures and functions of proteins and thus permit the generation of novel designed systems for both biocatalytic and mechanistic studies. Four complementary approaches are discussed in detail along with examples of their application. The advantages and disadvantages of each technique are also discussed.
Related Concept Videos
What are Proteins?
Peptide Bonds
Amino Acid Biosynthetic Pathways
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Proteins: Dietary Sources and Requirements
Proteins: From Genes to Degradation
Transcription is the synthesis of RNA molecules by RNA...

