Related Experiment Video
Updated: Aug 22, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
Regenerative therapy of furcation defect
1Department of Periodontology and Diseases of the Oral Mucosa, Faculty of Dentistry, Sofia.
Abstract:
Furcation defects of multiple-root teeth are complications of progressive periodontal diseases. The recommended technique of regenerative therapy in furcation defects of the lower molars is implantation of hydroxylapatite or demineralized freeze-dried bone. A case of a completely absent interradicular bone of 46 tooth in a 35-year-old woman with generalized periodontitis is presented. After endodontic treatment and recovery of the tooth crown we undertook surgical treatment of the bone defect: open curettage, using the technique of Ramfjord and bony reconstruction with aloplastic material bioplant HTR (septodont). The preoperative preparation included clinical prophylaxis and chemical plaque inhibition; postoperatively, rinsing the mouth twice a day with 0.5% metronidazole. The patient was followed up clinically and radiographically up to the 6th month after treatment when the bone structure regenerated.
Related Concept Videos
Overview of Regeneration and Repair
Regeneration
All animals have varying degrees of...
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
