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Updated: Aug 22, 2026

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
Published on: November 1, 2018
Focal segmental glomerulosclerosis in solitary kidney in WAGR syndrome
M Merta1, J Reiterová, M Krkavcová
1First Internal Department, First Faculty of Medicine, Charles University in Prague, Czech Republic. merta@mbox.cesnet.cz
Abstract:
WAGR syndrome consists of Wilms' tumour, aniridia, genitourinary malformations and mental retardation, and is associated with chromosomal microdeletion of 11p13. We report a case of young male, exhibiting several typical features of WAGR syndrome (e.g. WT, aniridia and genitourinary abnormalities), but missing some other (mental retardation and chromosomal abnormality absent). Renal biopsy performed in our patient for unexplained proteinuria showed focal segmental glomerulosclerosis, presumably of secondary origin; the decrease of proteinuria was achieved by the firm control of BP in conjunction with the reduction of body weight.
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