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Updated: Jul 30, 2026

Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Basal cell carcinoma arising in a port-wine stain
Sirunya Silapunt1, Leonard H Goldberg, Marzieh Thurber
1DermSurgery Associates, Houston, Texas 77030, USA.
Background:
The occurrence of basal cell carcinoma within a port-wine stain or nevus flammeus is rare. Sixteen cases of basal cell carcinoma which developed in a port-wine stain or nevus flammeus have been reported.
Objective:
The objective was to demonstrate a rare case of basal cell carcinoma occurring in a port-wine stain successfully treated with Mohs micrographic surgery.
Methods:
This is a case report and literature review.
Results:
An 87-year-old man presented with a basal cell carcinoma on the margin of a previously untreated port-wine stain on the left cheek. Histologic examination showed a nodular basal cell carcinoma. The basal cell carcinoma was completely excised with Mohs micrographic surgery and complex linear closure was used to repair the wound in layers. The postoperative course was complicated by a hematoma, which developed 24 hr postoperatively. The hematoma was drained and there was no further bleeding or evidence of recurrence of the tumor after 12 months.
Conclusion:
Basal cell carcinoma should be included in the differential diagnosis of a skin lesion occurring in a port-wine stain.
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