Related Experiment Video
Updated: Aug 22, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Will the new cytogenetics replace the old cytogenetics?
M Salman1, S C Jhanwar, H Ostrer
1Human Genetics Program, Department of Pediatrics, New York University School of Medicine, New York, NY 10003, USA.
Abstract:
With the advent of array-based comparative genomic hybridization technology, the analog cytogenetic analysis that has been used for the past 100 years could be replaced by the quantitative, microarray-based molecular analysis. Major advantages of the new array-based cytogenetic technologies are the high resolution and the high throughput. This technology is the first to offer an autonomous whole-chromosome analysis in one hybridization reaction for the detection of submicroscopic gains/losses. However, as with any new technology, it needs to be validated with regard to its performance in various applications (e.g. clinical genetic testing and cancer applications), comparative cost, and the data interpretation.
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