Leptin, bone mass, and the thrifty phenotype

Conditional Knockout of Indoleamine 2, 3-Dioxygenase-1 in Osteoprogenitor Cells in Mice Results in Sex-dependent Differences in Bone Mass.

Biochimie·2026

Tryptophan metabolites 3-hydroxykynurenine (3HK) and 3-hydroxyanthranilic acid (3HAA) increase oxidative stress and impair osteoblastic bone formation.

The Journal of biological chemistry·2026

The antiretroviral drug emtricitabine increases kynurenine: tryptophan ratio, aryl hydrocarbon receptor activation, and cellular senescence in female mice.

Biochimie·2025

The anti-retroviral therapy emtricitabine affects skeletal muscle DNA methylation and transcriptome patterns in a male HIV mouse model.

bioRxiv : the preprint server for biology·2025

Effects of two longevity interventions, calorie restriction and rapamycin treatment, on the kynurenine-aryl hydrocarbon receptor pathway in aging skeletal muscle.

Biochimie·2025

Inhibition of AhR improves cortical bone and skeletal muscle function via preservation of neuromuscular junctions.

JCI insight·2025

HR-pQCT measures of bone in autosomal dominant osteopetrosis highly correlate with fractures and inversely correlate with bone resorption markers.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026

Bone phenotype in a mouse model of Classical Ehlers Danlos syndrome with Col5a1 haploinsufficiency.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026

Programmed cell death ligand 1 (PD-L1) inhibition in tumor naïve mice is bone-sparing throughout the lifespan.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026

Abnormal position of a GNAS methylation regulatory element causes autosomal dominant pseudohypoparathyroidism type 1B (PHP1B).

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026

Increased Prevalence of Coronary Artery Calcification in Patients with Post-Surgical Hypoparathyroidism.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026

Alendronate for 6 or 12 months following denosumab discontinuation in women with postmenopausal osteoporosis: A prospective observational study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026

Mogroside-Rich Monk Fruit Extract Improves Glycemic Control Without Promoting Additional Weight Gain Compared With Sucralose and Sucrose in High-Fat Diet-Induced Obese Mice.

Food science & nutrition·2026

Affective factors predicting Binge Eating Disorder: The role of emotion regulation, impulsivity, and cognitive distortions.

Dusunen adam : Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi yayin organi·2026

Temporal gut microbiota dysbiosis links metabolic impairment, LDL desialylation, and accelerated atherosclerosis in LDLR<sup>-</sup>/<sup>-</sup> mice.

Frontiers in medicine·2026

Friend or Foe: Dietary Restriction and Its Protective Effects on Responses to Ionizing Radiation.

Dose-response : a publication of International Hormesis Society·2026

The effects of 12-weeks resveratrol supplementation on cognition, gastrointestinal microbiota, and systemic inflammation, in an overweight and obese human population: a randomized, double-blind, placebo controlled, parallel groups trial.

Frontiers in nutrition·2026

Dietary pattern modifies associations between dietary factors and pace of epigenetic aging.

Frontiers in nutrition·2026

Related Experiment Videos

Leptin, bone mass, and the thrifty phenotype

Related Concept Videos

Conditional Knockout of Indoleamine 2, 3-Dioxygenase-1 in Osteoprogenitor Cells in Mice Results in Sex-dependent Differences in Bone Mass.

Tryptophan metabolites 3-hydroxykynurenine (3HK) and 3-hydroxyanthranilic acid (3HAA) increase oxidative stress and impair osteoblastic bone formation.

The antiretroviral drug emtricitabine increases kynurenine: tryptophan ratio, aryl hydrocarbon receptor activation, and cellular senescence in female mice.

The anti-retroviral therapy emtricitabine affects skeletal muscle DNA methylation and transcriptome patterns in a male HIV mouse model.

Effects of two longevity interventions, calorie restriction and rapamycin treatment, on the kynurenine-aryl hydrocarbon receptor pathway in aging skeletal muscle.

Inhibition of AhR improves cortical bone and skeletal muscle function via preservation of neuromuscular junctions.

HR-pQCT measures of bone in autosomal dominant osteopetrosis highly correlate with fractures and inversely correlate with bone resorption markers.

Bone phenotype in a mouse model of Classical Ehlers Danlos syndrome with Col5a1 haploinsufficiency.

Programmed cell death ligand 1 (PD-L1) inhibition in tumor naïve mice is bone-sparing throughout the lifespan.

Abnormal position of a GNAS methylation regulatory element causes autosomal dominant pseudohypoparathyroidism type 1B (PHP1B).

Increased Prevalence of Coronary Artery Calcification in Patients with Post-Surgical Hypoparathyroidism.

Alendronate for 6 or 12 months following denosumab discontinuation in women with postmenopausal osteoporosis: A prospective observational study.

Mogroside-Rich Monk Fruit Extract Improves Glycemic Control Without Promoting Additional Weight Gain Compared With Sucralose and Sucrose in High-Fat Diet-Induced Obese Mice.

Affective factors predicting Binge Eating Disorder: The role of emotion regulation, impulsivity, and cognitive distortions.

Temporal gut microbiota dysbiosis links metabolic impairment, LDL desialylation, and accelerated atherosclerosis in LDLR<sup>-</sup>/<sup>-</sup> mice.

Friend or Foe: Dietary Restriction and Its Protective Effects on Responses to Ionizing Radiation.

The effects of 12-weeks resveratrol supplementation on cognition, gastrointestinal microbiota, and systemic inflammation, in an overweight and obese human population: a randomized, double-blind, placebo controlled, parallel groups trial.

Dietary pattern modifies associations between dietary factors and pace of epigenetic aging.

Related Experiment Videos

Leptin, bone mass, and the thrifty phenotype

Related Concept Videos

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