Related Experiment Video
Updated: Aug 15, 2026
Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats
Published on: December 5, 2017
[Endothelium contributes to the decreased aortic contractility in response to norepinephrine in experimental septic
1Institute of Basic Medical Sciences, Beijing.
Abstract:
The responses to norepinephrine of thoracic aortic rings from septic and sham operated rats were compared. Rings with endothelium taken from septic rats manifested significantly lower maximal contractile response to norepinephrine (575 +/- 46.1 mg) in comparison with sham operated tissues (775 +/- 54.7 mg). Tissues without endothelium showed no significant difference. The results suggest that the diminished responsiveness to norepinephrine of the thoracic aorta in septic rats is mediated, at least in part, by vascular endothelium.
More Related Videos
08:41Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
Published on: June 3, 2019
09:47Measurement of Endothelium-Dependent Vasorelaxation in the Mouse Thoracic Aorta Using Tensometric Small Volume Chamber Myography
Published on: August 12, 2022
